Stable disease meaning. Positioning/Pros & Cons.
Stable disease meaning Your coronary arteries gradually Also known as 'effort angina', this refers to the classic type of angina related to myocardial ischemia. Progression-free interval. Classification of CAD: 1) Stable CAD (chronic coronary syndrome): a) Stable Jul 5, 2020 · This is called complete response (CR), partial response (PR), stable disease (SD) and progressive disease (PD). But it is Jan 20, 2008 · However, for any given treatment, many more patients typically achieve stable disease (SD) or have progressive disease (PD) than achieve response. Oct 4, 2022 · Stable disease: A tumor has essentially not changed, and there is neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for PD, taking as reference the smallest sum diameters while on study. Subclinical disease May 7, 2015 · The exact meaning of the medical terminology,'Stable Disease' - Cancer that is neither decreasing nor increasing in extent or severity, is clearly explained in Medindia’s glossary of medical terms Partial Remission connotes cancer that is not actively growing over a period of time, also considered a stable disease. The only thing that should be made clear in such studies is Progressive Disease definition, namely, the protocol must contain the detailed description of findings that would be classified as the disease ÐÏ à¡± á> þÿ Ÿ þÿÿÿ Jan 22, 2015 · Fifty-nine percentage had progressive disease (PD), 26 % had stable disease (SD) and 15 % had an objective complete (CR) or partial response (PR). Mortality associated with CHD is mainly due to CAD. This is particularly important in the relapsed and refractory setting, where therapies are often associated with a minimal to nil response but may still confer a survival advantage, as is illustrated in the * Progressive Disease (PD): At least a 20% increase in the sum of the LD of target lesions, taking as reference the smallest sum LD recorded since the treatment started or the appearance of one or more new lesions * Stable Disease (SD): Neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for PD, Stable Disease. In this report, we sought to bring attention to the common and complex issue of “stable disease” and develop a strategy to use existing radiological measures to define response in this scenario. Apr 12, 2007 · In patients with stable coronary artery disease, it remains unclear whether an initial management strategy of percutaneous coronary intervention (PCI) with intensive pharmacologic therapy and lifes Heart disease. In asymptomatic or oligosymptomatic disease, SD is a good parameter for disease control and thus often for palliation. Chronic kidney disease. Of course, “stable disease” means different things for different patients, but for me it’s a very good thing. Remissions are often maintained for long periods of time with continuous or "maintenance" therapy. MedGen UID: 151811 • Concept ID: C0677946 • Finding. These topics were discussed in seven working groups representing different geographical regions. Feb 26, 2015 · This last CT examination showed stable disease progression for lung and skeletal localisations with no signs of a loco-regional recurrence. While partial remission, complete remission, and NED are all great news to cancer patients and their doctors, partial Remission vaguely implies that they are not “out of the woods. Refractory disease A refractory disease is a disease that resists treatment, especially an individual case that resists treatment more than is normal for the specific disease in question. The Stable Ischemic Heart Disease Clinical Topic Collection gathers the latest guidelines, news, JACC articles, education, meetings and clinical images pertaining to its cardiovascular topical area — all in one place for your convenience. Complete response, partial response, or stable disease: Cannot have met criteria for progression before complete response, partial response, or stable disease: Can have had iUPD (one or more instances), but not iCPD, before iCR, iPR, or iSD: Confirmation of complete response or partial response: Only required for non-randomised trials: As per Interstitial Lung Disease (ILD) refers to a group of problems in the lung that affects the “interstitium”. With cancer, stable disease means that tumours stay about the same size and no new tumours appear. However, if left untreated, tumors grow exponentially, implying that pretreatment changes in tumor size are key to thoroughly assess efficacy. [from NCI] Jul 1, 2009 · The scientific term is “disease progression”, but the reality is that the cancer is growing despite the treatment and it doesn’t take an expert to know that isn’t good news. What is hemodynamic instability? Hemodynamic instability means your body can’t get enough blood flow. INTRODUCTION Chronic Obstructive Pulmonary Disease (COPD) repre-sents a serious disease or, more precisely, a heterogeneous syndrome, affecting hundreds of millions of people world - wide1. What does my microsatellite stability result mean? If you have the MSS biomarker, this means that your cells can correct the errors that occur in DNA (DNA mismatch repair). People with heart disease are at higher risk for kidney disease, and people with kidney disease are at higher risk for heart disease. More information is given in the article RECIST 1. But I’ve lived a lot longer than I was supposed to, hearing “stable disease” every six weeks. Aug 28, 2024 · The combination of atezolizumab (atezo; anti–PD-L1 antibody) and bevacizumab (bev; antivascular endothelial growth factor antibody) has become the first-line standard treatment for advanced hepatocellular carcinoma (HCC) since 2020. ClassificationTop. Generally, a tumor would be expected to continue growing. ” Coronary artery disease types. However, next in line in the statements that seem to generate a decided lack of enthusiasm is “Your cancer is stable”. Nov 25, 2024 · When younger people get CKD, the disease tends to worsen, whereas people older than 65 years tend to have stable disease. Coronary heart disease (CHD), also known as ischemic heart disease (IHD), encompasses conditions such as stable angina, acute coronary syndrome (ACS), and silent myocardial ischemia. An Apr 17, 2024 · There are varying degrees in the response of a cancerous tumour to a treatment. In the case of chronic cancers, recurrence and progression can mean much the same thing. 1. It comes back together in a specific order because the base pairs can only match up in that specific order. Flow Chart of Management of Stable COPD 12. with certain taxane compounds or angiogenesis inhibitors), the cytological confirmation of the neoplastic origin of any effusion that appears or worsens during treatment can be considered if the measurable tumour has met criteria for response or stable disease in order May 1, 2011 · Thus, we suggest that the T2/FLAIR component of the TPR stable disease definition should be compared with either baseline or best response, to maintain consistency. Apr 3, 2018 · In clinical trials for solid tumors, the tumor is said to have responded if it shrinks by more than 30 percent. However, in t … Stable disease is characterized by the absence of significant changes in the size of pre-existing lesions and the absence of new tumor lesions. Stable disease could still mean that cancer has responded, for example, if cancer would have been expected to get worse but has Aug 21, 2024 · Critical condition, serious condition, stable: What do these terms mean? Learn how hospitals describe patients' condition to the press and public. Cancers that aren’t changing may be called stable disease. 1,2 In addition to a complete response (CR) rate of 8% for atezo-bev, the regimen often results in a high disease control rate and a sustainable response duration. Background: 'Stable disease (SD)' as per RECIST is a common but ambiguous outcome in patients receiving immune checkpoint inhibitors (ICIs). We hypothesized that existing objective measures of response may be able to define a subgroup of “SD responders” (SD-R), the subset benefiting Stable disease . We hypothesized that existing objective measures of response may be able to define a subgroup of ‘SD responders’ (SD-R), the subset benefiting Dec 31, 2020 · Conversation analysis was conducted on 112 video recorded and transcribed oncology interviews involving 30 doctors. The response categories are complete response, partial response (30% decrease in sum of length diameters -SLD from baseline), stable disease and progressive disease (20% increase in sum from baseline or Nadir). Ischemia can cause chest pain or discomfort known as angina pectoris Sep 29, 2023 · Cancers that aren’t changing may be called stable disease. When cancer grows, spreads, or gets worse it’s called progressive disease. What is ‘stable disease’ in multiple myeloma? Hi, Rafael Fonseca here, I am frequently asked what constitutes stable disease in the context of myeloma. Chronic coronary syndrome: Overview of care - UpToDate Although tumor dormancy, characterized by stable tumor status or stable disease (SD) without tumor regression, is a unique feature of sorafenib treatment, the contribution of SD to OS remains debatable. Sep 18, 2018 · Bibasilar atelectasis is a condition caused by a partial collapse of your lungs. Obesity can lead to type 2 diabetes and high blood pressure. Fatty liver disease starts with simple steatosis, also known as fatty change, which can progress to more advanced stages, such as steatohepatitis, fibrosis, and, ultimately, cirrhosis. Aug 6, 2019 · Stable ischemic heart disease (SIHD) is a leading cause of death in the United States and many other countries. 2 months for stable disease, while the Jan 6, 2025 · Fatty liver disease is one of the most common causes of chronic liver disease in the developed world, affecting up to one in every four individuals. Dec 5, 2022 · You may have heard the term “angina pectoris” (or “stable angina”). In the setting of advanced lung cancer, stable disease provides significant benefit to the patient. Other criteria have been published for these Mar 6, 2023 · What does “instability” mean in microsatellites? When DNA breaks apart to replicate and the reforms, it works a bit like a zipper. When arteries narrow, less blood and oxygen reach the heart muscle. Time from diagnosis or start of therapy Since the restriction to the measurable disease may slow down the recruitment to the study, trials often allow to entry both types of patients. Stable disease: The cancer has stayed the same size, it hasn’t got better or worse: Disease progression: The cancer has grown by at least a fifth (20%) or there are new areas of cancer: Overall response rate (ORR) The total number of people whose cancer has either gone away (a complete response) or shrunk (a partial response) SD - Stable Disease. [5] [6] [14] It is the most common of the cardiovascular diseases. The cytostatic, molecular-targeted therapies becoming available for lung cancer and other human solid tumors are more likely to result in stable disease than to produce tumor regression. If it hasn't grown, it can mean the treatment Stable disease is a category which is not included in the evaluation of the overall treatment response rate. Microvascular ischemic disease affects about 5% of people who are 50 years old. Larger tumor volumes and total treatment volumes correlated with worse cranial nerve function. We would like to show you a description here but the site won’t allow us. 1 in more detail and discuss other response systems. Your cancer cells have proficient mismatch repair. 8 months for all patients with available survival data; patients with PD had a median survival of 7. 11. Cancer that is neither decreasing nor increasing in extent or severity. A complete response corresponds to the disappearance of all detectable signs of cancer in the body, while a partial or incomplete response is a decrease in the size of the tumour or in the amount of cancer in the body. Jan 31, 2023 · Stable disease means your treatments are causing your tumor(s) to either not grow or shrink while no new tumors are developing. In other words, it hasn't grown significantly or decreased significantly in size. Too much body fat is bad for overall health. Furthermore, as has been previously noted, “we should not rush to falsely define drugs as active on the basis of stable disease, since stable disease is a composite outcome consisting of inherent tumor growth kinetics and potential drug effect. This can lead to heart attack. at least 20% relative and 5 mm absolute increase of SOD of target lesions compared to smallest SOD ever recorded for the patient. Time from start of treatment (or random assignment in a randomized trial) to progression. As a quantitative parameter, EORTC PET criteria use the mean standardized uptake value (SUVmean), normalized to the Reporting SD tends to obscure this fact. Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. No secondary localisations in the liver or brain were observed. Patients are considered stable if they are asymptomatic or their symptoms … Progressive Disease (PD) is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study (this includes the baseline sum if that is the smallest on study). If you have stable disease, you may wonder how often you should receive monitoring. Microsatellite stable is the most common result for this biomarker test. PFS, first of all, has the advantage of taking into account not only responsive disease, but stable disease as well (Table 1; ref. The primary aims of the study were: (1) to clarify the clinical significance of SD by comparing the progression-free survival (PFS) of response and SD patients with advanced non-small cell lung cancer (NSCLC) after the first two courses of the May 11, 2024 · non-progressive disease of non-target lesions. There is no cure for CKD , but early diagnosis and treatment can help stop Oct 18, 2023 · What is the life expectancy for a demyelinating disease? Demyelinating diseases can affect your life expectancy, but many don’t have a direct impact on how long you’ll live. Oct 13, 2023 · Other names for CAD include coronary heart disease (CHD) and ischemic heart disease. Conclusions The RANO criteria and guidelines are a needed advance over the formerly widely adopted Macdonald criteria. In this era of precision oncology, there has been an exponential growth in the armamentarium of genomically targeted therapies and immunotherapies. The interstitium refers to the tissue area in and around the wall of the airsacs (alveoli) of the lung area where oxygen moves from the alveoli into the capillary network (small blood vessels) that covers the lung like a thin sheet of blood. Equivalent to Objective Response Rate (ORR) Prognosis (Greek: πρόγνωσις "fore-knowing, foreseeing"; pl. This is followed by appropriate noninvasive testing guided by the probability of disease. 1 and more in which we will discuss RECIST 1. Your outlook (prognosis) is better if your disease isn’t getting worse (it’s stable). This study aimed to clarify the correlation between SD periods and OS in patients with HCC treated with sorafenib. Stable doesn’t sound so bad, does it? Mar 15, 2018 · Stable coronary artery disease refers to a reversible supply/demand mismatch related to ischemia, a history of myocardial infarction, or the presence of plaque documented by catheterization or Referring to a disease that is neither increasing nor decreasing in extent or severity. A disease that is neither decreasing nor increasing in extent or severity. It happens when the small air sacs called alveoli in your lungs deflate. ” 22 Jul 5, 2020 · The criteria to determine whether a tumor disappears, shrinks, stays the same or gets bigger are complete response (CR), partial response (PR), stable disease (SD) and progressive disease (PD). Recist 1. Nadir is the best result during therapy with the smallest SLD. Dec 2, 2018 · Not every patient will be told they’re in remission. A few millimeters on a scan is typically considered not to be clinically significant. Definition. Jun 14, 2024 · Type 2 diabetes and coronary artery disease share some risk factors, such as obesity and high blood pressure. Neither improving nor worsening. [15] As suggested by an international panel of experts, the conference focused on four topics: classification and nomenclature; definition of stable disease; definition of Koebner’s phenomenon (KP); and ‘autoimmune vitiligo’. 3. Panel B shows restricted mean durations of CR, PR, and stable disease in immune checkpoint inhibitor and placebo groups of scenario II. The opposite of progressive disease is stable disease or static disease: a medical condition that exists, but does not get better or worse. Nov 22, 2024 · Stable Disease . g. The chances of having the condition increase with age. A Mar 15, 2018 · Stable coronary artery disease refers to a reversible supply/demand mismatch related to ischemia, a history of myocardial infarction, or the presence of plaque documented by catheterization or computed tomography angiography. This is known as shock. We present a model-based approach to estimate the rates of changes in Dec 12, 2020 · Coronary artery disease (CAD) is characterized by the development of atherosclerosis in the coronary arteries, which can sometimes be asymptomatic. This most frequently is seen when long-standing atherosclerotic obstruction within the epicardial coronary arteries results in poor flow and ischemia How is stable disease determined?"Genetic" and "immunological" systems as well as the "microenvironment" of the tumor and host can, "spontaneously" or "induced by pharmacological agents", determine SD. The disease is associated with significant mortality,. Adenine (A) and thymine (T) can only pair with each other. Specifically, it means that there was neither an increase in size of more than 20% nor a decrease in size of more than 30% since the initial baseline measurement. Define Stable Disease. Who does microvascular ischemic disease affect? Microvascular ischemic disease occurs in older adults, affecting both males and females equally. The mean undertreated tumor volume was 0. In this article we describe the five easy steps to follow when you want to use RECIST 1. I’m not sure what to expect re: recurrence, but that’s because my cancer is horrendously understudied. Obesity. Some people with mild ILD can live normal lives without treatment or with minimal treatment. Stable disease can be a positive sign during treatment. 1 is not used for lymphoma, GIST during Glivec therapy, HCC and malignant brain tumors. When cancer grows, spreads, or gets worse it’s called cancer progression. Nov 11, 2024 · Chronic coronary disease (CCD) is initially evaluated with a thorough history, including chest discomfort and related symptoms, and assessment of risk factors. There are several types, depending on the cause. 03 cc in those with stable disease. Jul 20, 2021 · Stable disease (SD) means that the level of monoclonal protein neither decreased nor increased. Dec 11, 2024 · What is ischemic heart disease? Ischemic heart disease is heart damage caused by narrowed heart arteries. EORTC PET response criteria and PERCIST follow the model of RECIST and define 4 response categories: Complete metabolic response (CMR), partial metabolic response (PMR), stable metabolic disease and progressive metabolic disease. Overall survival. CAD can be classified as stable or unstable, depending on the clinical manifestations of the disease. Evaluating early responses to precision therapy is essential for “go” versus “no go” decisions for these molecularly targeted drugs and agents that arm the immune system. MSS occurs in 85% of all colorectal cancers. May 6, 2022 · ‘Stable disease (SD)’ as per RECIST is a common but ambiguous outcome in patients receiving immune checkpoint inhibitors (ICIs). This is also called coronary artery disease and coronary heart disease. There are two main forms of coronary artery disease: Stable ischemic heart disease: This is the chronic form. Stable Disease synonyms, Stable Disease pronunciation, Stable Disease translation, English dictionary definition of Stable Disease. Ask your healthcare team what a healthy weight is for you. In response, patients rarely affirm stable as good news for them. Stable disease means that the cancer hasn't changed significantly in either direction. We hypothesized that PD (or its converse, disease control rate [DCR], consisting of CR, PR, SD) is a stronger predictor of survival than response alone in advanced non–small-cell lung cancer (NSCLC Jul 24, 2023 · The term stable ischemic heart disease (SIHD) often is used synonymously with chronic coronary artery disease (CAD) and encompasses a variety of conditions where the end result is a repetitive mismatch between myocardial oxygen supply and demand. progressive disease (PD): either one of: any new lesions. In many studies with a response rate below 20%, chemotherapy almost doubles the survival of patients. When cancer comes out of remission it’s said to have progressed. A typical presentation of stable angina is that of chest discomfort and associated symptoms precipitated by some activity (running, walking, etc. Median overall survival was 16. The definition of stable disease is clarified as follows: “Neither sufficient shrinkage (compared to baseline) to qualify for partial or complete response (CR or PR) nor sufficient increase (taking as reference the smallest sum of diameters at baseline or while on study, whichever is smallest) to qualify for progressive disease (PD)”. The same is true for cytosine (C) and The sum of restricted mean durations of CR and PR is restricted mean duration of response. Interval between achieving a complete remission and recurrence or death, whichever occurs first. Many different response assessment criteria exist for use in solid May 28, 2021 · When patients remain progression free, their response statuses over time are CR, PR, or stable disease, and one can similarly partition restricted mean PFS into states of durations of CR, PR, and stable disease using the Q-TWiST method. ” May 12, 2021 · What’s the difference between remission, cancer-free, and no evidence of disease? A lot of people use those terms synonymously, but “remission” and “no evidence of disease” (also known as NEOD or NED) are probably the closest by definition. n. Small vessel ischemic disease. Positioning/Pros & Cons. Disease-free survival. Stable Disease refers to a situation where a disease, especially cancer, neither grows nor shrinks significantly following treatment. Panel A shows restricted mean durations of CR, PR, and stable disease in immune checkpoint inhibitor and placebo groups of scenario I. Research shows a link between kidney disease and heart disease. Definition of stable and unstable angina Stable coronary artery disease (angina pectoris) In classical angina pectoris, the pain is typically localized near the sternum. Future directions and developments 1. stable disease (SD): not meeting criteria for PD or PR Jul 20, 2023 · New recommendations for beta-blocker use in patients with CCD: (a) Long-term beta-blocker therapy is not recommended to improve outcomes in patients with CCD in the absence of myocardial infarction in the past year, left ventricular ejection fraction ≤50%, or another primary indication for beta-blocker therapy; and (b) Either a calcium channel blocker or beta blocker is recommended as first In this report, we sought to bring attention to the common and complex issue of “stable disease” and develop a strategy to use existing radiological measures to define response in this scenario. no new lesions. This study aimed to characterize SD and identify the subset of patients with SD who are benefiting from treatment. So, what is it, and what could it mean for you? It’s important to understand the basics. When cancer comes out of remission, it’s said to have progressed. Angina pectoris is the medical term for chest pain or discomfort due to coronary heart disease. : prognoses) is a medical term for predicting the likelihood or expected development of a disease, including whether the signs and symptoms will improve or worsen (and how quickly) or remain stable over time; expectations of quality of life, such as the ability to carry out daily activities; the potential for complications and Apr 6, 2018 · Sclerotic lesions are spots of unusual thickness on your bones. Patients are said to have stable disease if the tumor decreases in size, but by less than 30 percent or if it doesn’t grow more than 20 percent. Officially, both mean that no cancer is currently detectable in the body. This chapter describes the evaluation and management of ischemic heart disease, which has evolved significantly over the past decade. Inferior wall ischemia/infarction may cause pain located primarily in the epigastrium. This has different meaning whether the patient is in a relapsed or refractory state versus a patient who is receiving therapy for front-line myeloma. Mar 8, 2023 · Cancer doctors use the term stable disease to describe a tumor that is neither growing nor shrinking. 16). 9 months compared to 38. Dec 14, 2010 · Stable disease (SD) has ambiguous clinical significance for patients according to the dominant Response Evaluation Criteria in Solid Tumours (RECIST). 12 Such a Q-TWiST partition allows one to obtain restricted mean DOCR, DOPR, and duration of stable disease RECIL Stable Disease; Stable Disease Definition Less Than 10 percent decrease or''less than or equal to''20 percent increase in the sum of longest diameters of target lesions. 5 cc in patients with disease progression and 0. [11] May 23, 2018 · In detail, the irRC consisted of immune-related complete response (irCR; complete disappearance of all lesions), immune-related partial response (irPR; reduction of greater than or equal to 50% in disease burden), immune-related stable disease (irSD; neither irCR nor irPR criteria met), and, last, immune-related progression of disease (irPD; an Oct 13, 2023 · Definition. It’s also what most people mean when they use the general term “heart disease. Researchers are working to better understand the relationship between kidney disease and heart disease. Aug 1, 2022 · In this report, we sought to bring attention to the common and complex issue of ‘stable disease’ and develop a strategy to use existing radiological measures to define response in this scenario. The defining pathobiology is an imbalance between the metabolic demands of the myocardium and its oxygen supply, which most often results from coronary artery atherosclerosis. In the most chemotherapy trials with advanced colorectal cancer patients, about 30-50% had stable disease. Despite the radiological stability of the disease, there was a progressive increase in CEA and CA15. It occurs when the heart muscle doesn't get as much blood as it needs. In particular, several clinical trials have documented the benefits of revascularization in patients with acute ischemic syndromes as well as the efficacy of medical therapy, including lifestyle modification in patients with stable coronary disease. In 44 of 112 (39 percent) interviews, doctors announced stable as good cancer news. We hypothesized that existing objective measures of response may be able to define a subgroup of “SD responders” (SD-R), the subset benefiting Aug 5, 2022 · The life expectancy for interstitial lung disease depends on the cause and severity. Several things can cause them, from bone infections to Nov 15, 2021 · Coronary artery disease (CAD) is also referred to as ischemic heart disease (IHD) and is usually due to atherosclerosis of a coronary artery. In some cases, it can be considered a good sign. On average, people with a demyelinating disease may have a slightly shorter life expectancy (a few years shorter) than people who don’t have this condition. Chronic microvascular ischemic disease. Family history of kidney failure. Pain may radiate to the back, neck, jaw, or arms. ) with minimal or non-existent symptoms at rest or after administration of sublingual nitroglycerin. This term is frequently used in the context of clinical trials and oncology to describe a patient’s response to therapy, indicating a steady state of illness without progression. Uncorrected stable congenital cardiac abnormality, asthma with exacerbation, poorly controlled epilepsy, insulin dependent diabetes mellitus, morbid obesity, malnutrition, severe OSA, oncologic state, renal failure, muscular dystrophy, cystic fibrosis, history of organ transplantation, brain/spinal cord malformation, symptomatic hydrocephalus Jan 1, 2009 · When effusions are known to be a potential adverse effect of treatment (e. This refers to the proportion of patients who, according to internationally recognized criteria for alleviating evaluation, achieve tumor relief (PR+CR) and stable disease (SD) after treatment and can maintain for the minimum duration requirement. After numerous treatments, a lung cancer patient explains their reaction to being told they have stable disease and will continue on maintenance therapy. 1. Slow growing cancers, for a natural distribution of disease growth rate, can easily appear to be relatively stable over short periods May 29, 2020 · Rationale The RECIST guideline defines four categories of response to treatment for cancer patients according to post-baseline changes in tumor burden, hence ignoring disease history. While they’re usually harmless, they can occasionally be cancerous. Incomplete response or stable disease (SD): Persistence of one or more non-target lesion(s) or/and maintenance of tumor marker level above the normal limits; Progressive disease (PD): Appearance of one or more new lesions and/or unequivocal progression of existing non-target lesions; Evaluation of best overall response The evidence that stable disease is a valid end point in many recent clinical trials is therefore discussed in this review and along with contemporary methods that bring some accuracy to the interpretation of stable disease within the context of clinical trial results. ACS is Jul 5, 2021 · Stable disease refers to a clinical condition in which tumor extension has neither increased (no PD) nor decreased (no CR or PR). Understanding SD would facilitate drug development and improve precision in correlative research. Some may be informed their disease is “stable,” meaning it hasn’t progressed, or that it has shrank, or grown, by only a small amount. uemu qebzqpr ifcd bfkujxrt qty ecfzlc szqq kglei luxr ewha